Pathology
for Dental Students
Study questions: Renal pathology
Answers are here.


1.Acute poststreptococcal glomerulonephritis is most likely to occur following

A)Enterocolitis
B)Hepatitis
C)Pyelonephritis
D)Pharyngitis


2.Massive proteinuria with generalized edema, hypoalbuminemia, and hyperlipidemia and hyperlipiduria
  are the components of clinical syndrome called

A)Nephritic syndrome
B)Nephrotic syndrome
C)Uremic syndrome
D)Tetralogy of Fallot


3.Acute glomerulonephritis is most often due to a

A)Bacterial infection
B)Genetic defect
C)Viral infection
D)Antigen-antibody reaction
E)Poison


4.Which of the following may cause tubulointerstitial kidney disease?

A)Ascending bacterial infection
B)Analgesic drugs
C)Both
D)Neither


5.The most common cause of acute renal failure (ARF) is

A)Acute glomerulonephritis
B)Acute pyelonephritis
C)Acute tubular necrosis
D)Acute urinary tract obstruction
E)Interstitial nephritis


6.Membranous glomerulonephritis may occur in association with

A)Systemic lupus erythematosus
B)Diabetes mellitus
C)Infections
D)No known cause
E)All of the above


7.All of the following are true regarding acute tubular necrosis (ATN) except

A)The critical event is tubular damage
B)It is characterized clinically by acute renal failure
C)Necrosis of tubular epithelium is present
D)Most patients do poorly and go on to suffer from end stage renal disease
E)One cause of ATN is severe glomerular disease


8.Which of the following diseases is characterized by subepithelial deposits within the glomeruli?

A)Minimal change disease
B)Membranous glomerulonephritis
C)Both
D)Neither


9.All of the following are true statements regarding acute pyelonephritis except

A)The most common causative agent is E. coli
B)The hematogeneous route is the most common pathway of infection
C)In ascending infections, organisms often gain access to bladder via intrumentaton (i.e.
   catheterization)
D)Obstruction is an important predisposing factor
E)Patients with diabetes mellitus have a greater number ofof complications secondary to
   pyelonephritis than non-diabetic patients


10.The most common malignant tumor of the kidney and urinary tract is

A)Renal cell carcinoma
B)Wilms' tumor
C)Transitional cell carcinoma
D)Medullary fibroma


11.Which of the following is true?

A)Glomerular diseases and tubulointerstitial diseases are usually immunologically mediated
B)Glomerular diseases and tubulointerstitial diseases are usually caused by infections or toxic agents
C)Glomerular diseases are usually caused by infectious or or toxic agents; tubulointerstitial diseases are
   usually immunologically mediated
D)Glomerular diseases are usually immunologically mediated; tubulointerstitial diseases are usually
   caused by toxic or infectious agents


12.Which of the following is characterized by massive proteinuria, hypoalbuminemia, edema, and
    hyperlipidemia?

A)Chronic glomerulonephritis
B)Nephritic syndrome
C)Nephrotic syndrome
D)Rapidly progressive glomerulonephritis
E)Uremic syndrome


13.The biochemical abnormality that refers to elevation of blood urea nitrogen and creatinine levels is called:

A)Cystitis
B)Nephrosis
C)Azotemia
D)Uremia


14.Post-streptococcal glomerulonephritis most often presents with which morphologic pattern of glomerular
    injury?

A)Membranoproliferative glomerulonephritis
B)Focal segmental glomerulosclerosis
C)Membranous glomerulonephritis
D)Mesangial proliferative glomerulonephritis
E)Diffuse proliferative glomerulonephritis


15.The most common bacterial organism causing acute pyelonephritis is

A)Proteus
B)E. coli
C)Staphylocci
D)Streptococci
E)Klebsiella


16.Autosomal recessive polycystic kidney disease

A)Numerous cysts develop and virtually replace normal renal parenchyma
B)Associated with congenital hepatic fibrosis
C)Both
D)Neither


17.All of the following are true regarding renal cell carcinoma EXCEPT:

A)Males are affected more often than females
B)It represents the most common type of renal malignancy
C)The cell of origin is the transitional epithelial cell
D)Tumor stage is an important prognostic indicator
E)It often presents with painless hematuria, long-standing fever and flank pain