Pathology
for Dental Students
Study questions: Hepatobiliary system pathology
Answers are here.

1.Cholangiocarcinoma (gallbladder carcinoma) is

A)Usually multifocal
B)Associated with cirrhosis
C)Associated with ulcerative colitis
D)Associated with gallstones


2.If you acquire hepatitis C from a patient, your risk of developing chronic hepatitis is approximately

A)10%
B)30%
C)50%
D)90%


3.The most frequent result of infection with hepatitis A virus is

A)Chronic active hepatitis
B)Massive hepatic necrosis
C)Hepatocellular carcinoma
D)Acute self-limited hepatitis


4.Complications of cirrhosis include all except

A)Esophageal bleeding
B)Liver failure
C)Ascites
D)Cholangiocarcinoma (gallbladder carcinoma)


5.Cryptosporidium infection

A)Occurs only in patients with AIDS
B)Is a common cause of hepatitis
C)Is easily treatable with antibiotics
D)May cause self-limited diarrhea


6.Formation of gallstones is related to all except

A)Alcohol abuse
B)Age
C)Race
D)Gender


7.Alcoholic hepatitis is characterized by all EXCEPT:

A)Fatty change
B)Accumulation of keratin in hepatocytes
C)A neutrophilic infiltrate in the lobule
D)Intranuclear inclusions


8.Hepatocellular carcinoma is

A)A relatively frequent tumor in the U.S. population
B)Associated with cirrhosis
C)Associated with ulcerative colitis
D)Associated with gallstones


9.All of the following cause chronic hepatitis EXCEPT:

A)Hepatitis A virus
B)Hepatitis C virus
C)Hepatitis B virus
D)Drugs


10.Which of the following types of gallstones is most likely to be found associated with
    chronic cholecystitis in the United States?

A)Cholesterol
B)Pigment
C)Black
D)Brown
E)Calcific


11.Bile cultures of which of the following types of cholecystitis are most likely to be positive?

A)Acute cholecystitis
B)Chronic cholecystitis
C)Sclerosing cholecystitis
D)Xanthogranulomatous cholecystitis
E)Cholecystitis associated with sclerosing cholangitis


12.In the U.S., cholangiocarcinoma (gallbladder carcinoma) is most frequent in

A)Caucasian males
B)Caucasian females
C)African-American females
D)Hispanic females
E)Native American females


13.Infection with hepatitis A virus may result in

A)Chronic active hepatitis
B)Massive hepatic necrosis
C)Hepatocellular carcinoma
D)Acute self-limited hepatitis


14.Alcoholic liver disease is characterized by

A)Mallory bodies
B)Piecemeal necrosis
C)Granuloma formation
D)Ground glass cells


15.In chronic cholecystitis

A)Adenocarcinoma develops in the majority of patients who have the disease for more than 20 years
B)E. coli and enterococci are cultured from the bile in 30% of cases
C)Gallstones are usually absent
D)Rupture of the gallbladder is a frequent complication
E)There is a good correlation between the number of stones and the severity of symptoms


16.Which disease is most commonly associated with the development of hepatocellular carcinoma?

A)Autoimmune hepatitis
B)Primary sclerosing cholangitis
C)Hepatitis B
D)Primary biliary cirrhosis


17.Steatohepatitis (fatty liver) is usually caused by which of the following injuries?

A)Obstruction to extrahepatic bile ducts
B)Alcohol abuse
C)Hemochromatosis
D)Hepatitis C
E)Superinfection with Hepatitis D virus


18.Which malignant tumor in the liver is the most frequent?

A)Metastatic carcinoma
B)Clear cell hepatocellular carcinoma
C)Cholangiocarcinoma
D)Fibrolamellar hepatoma


19.In the United States, cholesterol gallstones are

A)Present in more than 50% of females
B)More frequent in Native Americans than Caucasians
C)Frequently found in association with diabetes mellitus
D)Associated with other disorders such as hemolytic anemia, cirrhosis and alcoholism
E)Absent in most cases of acute cholecystitis


20.Complications of portal hypertension include all except

A)Ascites
B)Spontaneous bacterial peritonitis
C)Esophageal varices
D)Hepatic necrosis
E)Splenomegaly


21.The most common cause of portal hypertension in the U.S. is

A)Prehepatic cancer
B)Posthepatic cancer
C)Cirrhosis
D)Sarcoidosis


22.Hepatic adenomas

A)Usually progress to hepatocellular carcinoma
B)Are associated with oral contraceptives
C)Both
D)Neither