A patient is found to have a decreased hemoglobin and an increased mean cell volume (MCV). A.Iron deficiency B.ThalassemiaC.Anemia of chronic diseaseD.Vitamin B12 or folate deficiency All of the following statements are true regarding vitamin B12/folate deficiency anemia EXCEPT:A.It is characteristically a macrocytic anemiaB.Vitamin B12 stores in the body generally last for 3 months without replenishment C.The hallmarks of the blood smear include macrocytes (large red blood cells) and hypersegmented neutrophilsD.Folate deficiency anemia is frequently seen in chronically malnourished individuals such as alcoholicsYou prescribe penicillin for one of your patients. Three days later he returns to your office jaundiced. A.Iron deficiency anemiaB.ThalassemiaC.Drug induced autoimmune hemolytic anemia D.Hereditary spherocytosisA patient presents with a decreased hemoglobin and a decreased mean cell volume (MCV). The neutrophil and A.Vitamin B12 or folate deficiencyB.Aplastic anemiaC.Sickle cell anemiaD.Either iron deficiency or thalessemia Which of the following sets of lab values best fits sickle cell anemia? HemoglobinMCVReticulocytesA.decreased decreaseddecreasedB.normalnormal normalC.decreased increased decreasedD.decreased normal increased Which of the following sets of lab values best fits iron-deficiency anemia? HemoglobinMCVReticulocytesA.decreased decreaseddecreased B.normal normal normalC.decreased increased decreasedD.decreased normal increasedThe most common cause of neutropenia isA.Iron deficiencyB.Drug administration C.ThalassemiaD.Vitamin B12/folate deficiencyAll of the following are associated with the etiology of leukemias EXCEPT:A.VirusesB.Down SyndromeC.Char-broiled meat D.RadiationWhich of the following is true regarding leukemias:A.Acute myeloid leukemia (AML) is more common than acute lymphoblastic leukemia (ALL) in childrenB.Chronic myelogenous leukemia (CML) generally terminates in 3-5 years in a blast crisis C.CML is most common in childrenD.Acute leukemia is generally not accompanied by bone marrow failure (i.e. thrombocytopenia, anemia and neutropenia)Which of the following is or are true regarding acute myeloid leukemia (AML)?A.A patient with l5% myeloblasts in the blood or bone marrow can be diagnosed as having acute myeloid leukemia (AML)B.The myeloblasts typically express myeloperoxidase enzyme C.BothD.NeitherInfiltrates of the gingiva are particularly characteristic of which of the following leukemiasA.Chronic Myelogenous LeukemiaB.Acute Myelogenous Leukemia, monocytic subtype C.Acute Lymphoblastic Leukemia, precursor B-cell subtypeD.Chronic Lymphocytic Leukemia, B-cell subtypeWhich of the following statements is true regarding acute myeloid leukemia (AML)? A.Auer rods may be present B.A patient with 10% myeloblasts in the blood or bone marrow can be diagnosed as having acute myeloid leukemia (AML)C.AML occurs predominantly in childrenD.the myeloblasts are typically positive for B-cell lymphocyte antigensWhich of the following is true regarding acute lymphoblastic leukemia?A.A patient with 40% lymphoblasts in the bone marrow can be diagnosed as having acute lymphoblastic leukemia B.Lymphoblasts can always be differentiated from myeloblasts based on their morphologyC.Lymphoblasts typically express myeloperoxidase enzyme D.Acute lymphoblastic leukemia is more common in adults than childrenThe Philadelphia chromosome:A.Involves a translocation between chromosome 9 and 22 and is most often associated with chronic lymphocytic leukemia (CLL)B.Involves a translocation between chromosome 8 and 21 and is most often associated with chronic myelogenous leukemia (CML)C.Involves a translocation between chromosome 9 and 22 and is most often associated with chronic myelogenous leukemia (CML) D.Involves a translocation between chromosome 8 and 21 and is most often associated with acute myelogenous leukemia (AML)All of the following statements are true regarding myeloproliferative disorders EXCEPT:A.Splenomegaly is frequently present.B.Leukocytosis is frequently present.C.Children do not get chronic myeloid leukemia.D.A hypercellular marrow is frequently present.E.The presence of the Philadelphia chromosome in a myeloproliferative disorder is compatible with a diagnosis of polycythemia vera. All of the following statements are true regarding chronic lymphocytic leukemia (CLL) EXCEPT:A.CLL is an indolent leukemiaB.Most cases of CLL are of T-cell lineageC.The malignant lymphocytes in B-cell CLL express surface (membrane) immunoglobulinD.Patients with CLL have a lymphocytosisWhich of the following is true regarding Hodgkin's disease?A.It frequently arises in the intestinesB.It responds poorly to current chemotherapeutic regimensC.It tends to spread in a contiguous fashion D.Hodgkin's disease most commonly presents in patients over 60 years of ageA patient has Hodgkin's lymphoma involving only the cervical lymph nodes. This patient has:A.Stage I disease B.Stage II diseaseC.Stage III diseaseD.Stage IV diseaseAll of the following statements are true regarding lymphoma EXCEPT:A.Hodgkin's lymphoma generally has a good prognosisB.The malignant cell of Hodgkin's lymphoma is the Reed-Sternberg cellC.Left untreated, low grade lymphomas have an aggressive clinical course though they frequently can be cured by chemotherapy D.Follicular lymphomas are all B-cell lymphomasWhich of the following is a LOW grade lymphoma?A.Follicular lymphomaB.Diffuse, large B-cell lymphomaC.Burkitt lymphomaD.Anaplastic large-cell lymphomaWhich of the following is true regarding non-Hodgkin's lymphomas:A.Follicular lymphomas are high-grade lymphomasB.All diffuse lymphomas are B-cell lymphomasC.Most non-Hodgkin's lymphomas are of B-cell lineage D.They usually remain localized to a single nodal region of the bodyAll of the following statements are true regarding myeloma EXCEPT:A.Characterized by a clonal proliferation of plasma cellsB.Often produces lytic lesions especially of skullC.Bone marrow shows histiocytes with Birbeck granules D.Associated with amyloidosis