Pathology

for Dental Students

Study questions: Female reproductive system pathology

Answers are here.

1. Teratoma of the ovary originates in:

A.surface epithelial cells

B.germ cells

C.stromal cells

D.corpus luteum cells

E.Sertoli-Leydig cells

2. Cervical intraepithelial neoplasia (CIN) encompasses all of the following terms EXCEPT:

A.Moderate dysplasia

B.Invasive carcinoma

C.Severe dysplasia

D.Carcinoma-in-situ

3. Hydatidiform mole (complete or partial):

A.Is a benign form of gestational trophoblastic disease

B.Is characterized by increased levels of HCG

C.Is always related to pregnancy

D.May give rise to choriocarcinoma

E.All of the above

4. All of the following are true of endometrial carcinoma EXCEPT:

A.most cases occur in postmenopausal women

B.caused by prolonged stimulation of the endometrium by progesterone

C.preceded by endometrial hyperplasia in most cases

D.can metastasize via lymphatic and/or hemtogenous routes

E.the most important prognostic factor is the stage of the tumor

5. All of the following are true of squamous cell carcinoma of the uterine cervix EXCEPT:

A.it is preceded by squamous cell dysplasia in most cases

B.it appears to be caused by human papillomavirus (HPV)

C.early age at first intercourse is a risk factor

D.most cases of invasive squamous cell carcinoma occur in women over 65

E.the Pap smear is an important screening test

6. All of the following are true of ovarian neoplasms EXCEPT:

A.they are usually benign

B.they can become very large before causing symptoms

C.they may interfere with fertility

D.they are very rare

E.they may be cystic

7. True about leiomyoma of the uterus

A.Is often entirely asymptomatic

B.The most frequent manifestation is menorrhagia

C.Most probably never undergoes malignant transformation

D.All of above

E.None of above

8. The most important prognostic factor in cervical carcinoma

A.Histologic type of tumor

B.History of cervical dysplasia on pap smear

C.Clinicopathologic stage of tumor

D.Histologic grade of tumor

E.Age of onset

9. Endometrial hyperplasia:

A.Always progresses to endometrial carcinoma

B.Risk of developing malignancy is increased when atypia is present

C.Is related to relative or absolute hyperprogesteronism

D.Is a form of endometrial polyp

E.Is associated with HPV infection