Cell Injury and Adaptation (Chapter 1: Cell Injury, Cell Death, and Adaptation)
*Check out Dr. Dolan's powerpoint for references to specific pages and figures*
Pages 1-5: Check out Overview of Cellular Responses to Stress, the sections on Hypertrophy, Hyperplasia,
Atrophy, and Metaplasia, and Overview of Cell Injury and Cell Death.
Pages 7-17: Skim, look at pictures and diagrams.
Pages 18-20: Check out the sections on Ischemic and Hypoxic Injury, Ischemia-Reperfusion Injury, and Apoptosis.
Pages 20-22: Skim, look at pictures and diagrams.
Pages 23-27: Skim, look at pictures and diagrams.
Pages 28-29: Skip this.
Inflammation (Chapter 2: Acute and Chronic Inflammation)
Pages 31-35: These are good. Stop at Cellular Events: Leukocyte Recruitment and Activation.
Pages 35-40: Skim, look at pictures and diagrams.
Pages 40-42: Check out the sections on Leukocyte-Induced Tissue Injury and Outcomes of Acute Inflammation.
Pages 43-44: Check out the section on Morphologic Patterns of Acute Inflammation.
Pages 44-53: Scary. Skim a little, look at the diagrams. Table 2-4 would be good to review before boards (believe it or not,
there are actually questions on some of these chemical mediators and their actions.)
Pages 53-58: These are good.
Tissue Repair (Chapter 3: Tissue Repair: Regeneration, Healing, and Fibrosis)
Pages 59-62: These are good.
Pages 63-68: Skip this.
Pages 69-73: Skim this. Don't worry about all those growth factors.
Pages 74-78: These are good. Practical (how do wounds heal?) and good for boards.
Immune System (Chapter 5: Diseases of the Immune System)
Pages 108-118: These are good, but dense. Just get the main points so that later stuff makes sense.
Hypersensitivity Reactions (Chapter 5: Diseases of the Immune System)
Pages 119-131: These are good, but dense. Hypersensitivity questions come up on boards a lot.
Immunologic Laboratory Tests
Robbins doesn't have anything on this! First Aid for Part 1 of the Boards has a table on page 509.
Transfusion Pathology
Robbins doesn't have anything on this either. First Aid has a little bit on page 510.
Transplantation Pathology (Chapter 5: Diseases of the Immune System)
Pages 131-134: These are good, but skip the section on morphology.
Immune Diseases (Chapter 5: Diseases of the Immune System)
Pages 135-152: These pages cover autoimmune diseases. You can skip the sections on Morphology under lupus, rheumatoid
arthritis, Sjogren syndrome, and systemic sclerosis. You can also skip seronegative spondyloarthropathies,
inflammatory myopathies, mixed connective tissue disease, and polyarteritis nodosa.
Pages 152-155: These pages cover primary immune deficiencies. There's a lot of detail - you only need to know what we
covered in class for the exam.
Neoplasia (Chapter 6: Neoplasia)
Pages 174-185: Nomenclature, tumor characteristics, and epidemiology. These are good.
Pages 185-206: Molecular pathogenesis of cancer. Way way way too dense for our purposes. Look at diagrams, and read little
green summary boxes if you are so inclined.
Pages 206-214: Multistep process of carcinogenesis, chromosomal changes, and carcinogenic agents. These are pretty good
although too in-depth on the carcinogenic agents stuff.
Pages 218-219: Read the little section on Grading and Staging of cancer.
Cardiovascular Pathology (Chapter 10: The Blood Vessels, and Chapter 11: The Heart)
Pages 343-353: Atherosclerosis
Pages 357-362: Aneurysms
Pages 362-369: Arteritis/vasculitis
Pages 388-397: Ischemic heart disease
Respiratory Pathology (Chapter 13: The Lung)
This whole chapter is quite good. Most of it is relevant to our course.
Pages 480-502: Normal lung, atelectasis, acute lung injury, emphysema, chronic bronchitis, asthma, bronchiectasis, diffuse
interstitial fibrosis, pneumoconioses, sarcoidosis.
Pages 504-528: Pulmonary embolism, pulmonary hypertension, Goodpasture's syndrome, Wegener's granulomatosis, lung
infections (the section on TB is a bit too in-depth).
Pages 528-534: Lung tumors (just skim through the section on morphology)
Pages 534-536: Pleural lesions
Pages 536-538: Upper respiratory tract lesions (Dr. Powell doesn't cover these; just read through for your own edification)
Renal Pathology (Chapter 14: The Kidney)
Pages 541-542: General stuff on the kidney
Pages 542-544: General stuff on glomerular diseases
Pages 549-552: Nephrotic syndrome and the glomerular diseases that cause it (you can skip membranoproliferative
glomerulonephritis; we're not covering that one)
Pages 554-556: Nephritic syndrome and the glomerular diseases that cause it (skip hereditary nephritis, and the stuff that
Pages 559-563: Pyelonephritis
Pages 563-564: Interstitial nephritis
Pages 564-566: Acute tubular necrosis. This is really detailed. Just skim this.
Pages 566-567: Vascular stuff (skip thrombotic microangiopathies; we'll cover these in Bleeding and Thrombotic Disorders)
Pages 569-571: Cystic kidney disease
Pages 571-573: Kidney stones (we didn't cover this in class; read it for your own interest)
Pages 573-476: Renal and bladder cancers. Skim this, skipping the morphology sections and the genetic stuff.
Gastrointestinal Pathology (Chapter 15: The Oral Cavity and the GI Tract, Chapter 16: The Liver, Gallbladder, and Biliary Tract,
and Chapter 17: The Pancreas)
Pages 585-591: Esophagus
Pages 591-600: Gastritis, stomach ulcers, and stomach cancer
Page 600: Meckel diverticulum
Pages 603-604: Diverticulosis
Pages 605-609: Diarrheal diseases
Pages 609-611: Malabsorption syndromes
Pages 611-616: Inflammatory bowel disease
Pages 616-624: Colon cancer (skim the section on genes; it's too involved to really get into - just look at all the steps that need
to happen! It's a good example of the "multistep carcinogenesis" idea we talked about back in neoplasia.
Also, check it out: both RAS and p53 are mutated!)
Pages 632-633: General stuff, and patterns of hepatic injury
Pages 633-639: Clinical symptoms and consequences of liver failure
Pages 639-654: Hepatitis (viral, autoimmune, alcoholic, drug-induced)
Pages 654-657: Hemochromatosis and Wilson Disease
Pages 658-660: Primary biliary cirrhosis and primary sclerosing cholangitis
Pages 664-666: Liver tumors
Pages 667-669: Cholelithiasis and cholecystitis
Pages 675-676: General stuff about the pancreas
Pages 676-681: Acute and chronic pancreatitis
Pages 682-684: Pancreatic cancer
Female Reproductive Pathology (Chapter 19: The Female Genital System and Breast)
Pages 717-721: Cervical tumors
Page 722: Endometriosis
Pages 722-724: Endometrial hyperplasia
Pages 724-726: Uterine tumors
Pages 728-734: Ovarian tumors
Pages 739-741: Fibrocystic change of breast
Pages 742-749: Breast tumors
Male Reproductive Pathology (Chapter 18: The Male Genital System)
Pages 689-690: Cryptorchidism
Pages 690-695: Testicular neoplasms (skim or ignore the morphology section)
Pages 696-697: Nodular hyperplasia of the prostate
Pages 698-700: Prostatic carcinoma
Pages 700-709: STDs (skim)
Anemia (Chapter 12: The Hematopoietic and Lymphoid Systems)
Pages 422-440: These pages are good - but don't get too bogged down in the details.
Benign Leukocytoses (Chapter 12: The Hematopoietic and Lymphoid Systems)
Pages 442-443: Robbins is pretty sparse here, but you get the idea...
Acute Leukemia (Chapter 12: The Hematopoietic and Lymphoid Systems)
Pages 447-449: Acute lymphoblastic leukemia (which is the same thing as lymphoblastic lymphoma, as you'll see when we
get to the lymphoma lecture) is discussed here. This is pretty confusing the way it's written. Robbins
discusses hematopoietic malignancies in two big categories: lymphoid neoplasms (which include lymphoma,
acute lymphoblastic leukemia, and chronic lymphocytic leukemia) and myeloid neoplasms (which include
acute myeloid leukemia and chronic myeloid leukemia). We split them up differently in our course: we discuss
them in terms of their clinical appearance (acute leukemias, chronic leukemias, and lymphomas). Which I
think makes a lot more sense, because a patient doesn't come to you and say, "I've got a lymphoid
neoplasm!" but they do show signs of acute disease or chronic disease (which relate to acute leukemia and
chronic leukemia). Oh well. I guess they didn't ask me to write this section of the book.
Pages 461-463: Acute myeloid leukemia. You can skip the section on myelodysplastic syndromes; we aren't discussing
Chronic Leukemia (Chapter 12: The Hematopoietic and Lymphoid Systems)
Pages 450-451: Chronic lymphocytic leukemia
Pages 463-367: Chronic myeloid leukemia
Lymphoma and Myeloma (Chapter 12: The Hematopoietic and Lymphoid Systems)
Pages 445-453: Non-Hodgkin lymphoma. Skip the ones we didn't cover in class (unless you're just interested!)
Pages 453-456: Multiple myeloma
Pages 456-459: Hodgkin lymphoma
Pages 459-460: Two more non-Hodgkin lymphomas: Marginal zone (same as the MALT lymphoma we discussed in class,
and Mycosis fungoides/Sezary syndrome.
Hemostasis and Bleeding and Thrombotic Disorders (Chapter 4: Hemodynamic Disorders, Thrombosis and Shock, and
Chapter 12: The Hematopoietic and Lymphoid Systems)
Pages 86-99: General properties of hemostasis; thrombosis
Pages 468-475: Bleeding disorders
Skin Pathology
Nervous System Pathology
Developmental Pathology
Musculoskeletal Pathology
Endocrine Pathology
